Imran Tahir took 5-45 as West Indies were 151 all-out with heaviest World Cup defeat by runs.
Just a month ago, De Villiers hit the fastest-ever ODI hundred against the West Indies in Johannesburg, from 31 balls.
In that same innings, South Africa's caption likewise set the record for the fastest fifty in ODIs, from 16 balls.
The Proteas made a lazy begin and were 87-1 after 20 overs, before De Villiers went to the wrinkle in the 30th over with his side 146-3.
De Villiers put on 134 with Rilee Rossouw (61 from 39) and South Africa scored 222 from the last 15 overs, with De Villiers' 73 from the last five an alternate ODI record.
West Indies skipper Jason Holder's last two overs strove for 64 runs, with one over striving for 34. De Villiers completed with 17 fours and eight sixes, more than he had spot balls.
South Africa's aggregate was the most elevated by any group in Australia and just India's 413-5 against Bermuda at Port of Spain in 2007 (which additionally completed in a 257-run triumph for India) is higher in World Cups.
Hashim Amla (65) and Faf du Plessis (62) likewise made fifties for South Africa, while Holder, who yielded only nine runs in his initial five overs, completed with figures of 1-104 off 10, the most lavish in World Cup history.
West Indies opener Chris Gayle, who scored the first 200 in World Cups against Zimbabwe on Tuesday, scored just three preceding he was rocked the bowling alley by Kyle Abbott.
Rohit Sharma on Thursday comes back to International cricket with a great double hundred and shatters records in ODI against Sri Lanka at Kolkata's favourite Eden Gardens. He likewise turns into the first player to hit 250 and two double hundreds in an One Day International match. He scored his first ODI double against Australia last November in Bangalore.
The right-handed batsman got himself out off the last ball of the innings, attempting to clear the straight boundary. Be that as it may veteran Sri Lankan Mahela Jayawardene took a smooth catch off Nuwan Kulasekara. By then, he had effectively scored an amazing 264 races to turn into the highest scorer in an ODI innings. He is the third player, all Indian, to hit double hundreds in the 50-overs format. Others were batting greats Sachin Tendulkar and Virender Sehwag. 
Interestingly, all the four innings have come in India, all scored by Indian openers. Little Master was the first to accomplish the accomplishment, when he scored an unbeaten 200 (149 balls, 25 fours and seven sixes) against South Africa on 24 Feb 2010. Virender Sehwag turned into the second player to hit a double ton on December 8, 2011 against West Indies. He scored 219 with the help of 25 fours and seven sixes. Rohit Sharma's first double touched base on November 2, 2013 against Australia. He scored 209 off 158 balls.
The 27-year-old skilled batsman was making a rebound to the Indian One Day International squad after a injury lay-off. He keep going played for India on August 27 against England at Cardiff. During the England tour, he got injured with fracture on the center finger of his right hand.
With India having effectively won the five-match series against Sri Lanka, the Indian team management selected to turn and give playing time to whatever number players as would be prudent in front of the 2015 Cricket World Cup. In this manner, accumulated Rohit into the Indian fold.
India have won the initial three matches in Cuttack, Ahmedabad and Hyderabad. After today's Kolkata fixture, the last ODI will be played at Ranchi.
